Terminal · Institutions
Every 13F-reported equity position this quarter, with its quarter-over-quarter change — each row traces back to the SEC filing.
Every 13F-reported equity position this quarter, with its quarter-over-quarter change — each row traces back to the SEC filing.
Paradigm Biocapital Advisors LP (CIK 1855655) reported $5.34B across 28 reported positions in its SEC 13F filing for 2026-06-30. Largest positions: RVMD ($1.19B, 22.31%), NUVL ($731.7M, 13.70%), EWTX ($415.1M, 7.77%), GMAB ($360.8M, 6.76%), SYRE ($341.0M, 6.38%). Source: SEC Form 13F.
| Rank | Ticker | Company | Value | % Portfolio | Shares | Action |
|---|---|---|---|---|---|---|
| 1 | RVMD | REVOLUTION MEDICINES INC | $1.19B | 22.31% | 6.4M | Trimmed |
| 2 | NUVL | NUVALENT INC | $731.7M | 13.70% | 5.9M | Added |
| 3 | EWTX | EDGEWISE THERAPEUTICS INC | $415.1M | 7.77% | 10.2M | Added |
| 4 | GMAB | GENMAB A/S | $360.8M | 6.76% | 13.1M | Added |
| 5 | SYRE | SPYRE THERAPEUTICS INC | $341.0M | 6.38% | 3.8M | Added |
| 6 | APGE | APOGEE THERAPEUTICS INC | $209.2M | 3.92% | 1.6M | Added |
| 7 | ORKA | ORUKA THERAPEUTICS INC | $204.1M | 3.82% | 2.1M | Trimmed |
| 8 | TNGX | TANGO THERAPEUTICS INC | $198.7M | 3.72% | 6.4M | Added |
| 9 | BLTE | BELITE BIO INC | $189.8M | 3.55% | 1.2M | Added |
| 10 | ERAS | ERASCA INC | $175.0M | 3.28% | 9.6M | Trimmed |
| 11 | TARS | TARSUS PHARMACEUTICALS INC | $174.7M | 3.27% | 2.8M | Added |
| 12 | ALNY | ALNYLAM PHARMACEUTICALS INC | $144.5M | 2.71% | 480,000 | New |
| 13 | INSM | INSMED INC | $141.4M | 2.65% | 1.3M | Added |
| 14 | MBX | MBX BIOSCIENCES INC | $138.4M | 2.59% | 2.5M | New |
| 15 | PCVX | VAXCYTE INC | $123.7M | 2.32% | 2.1M | Trimmed |
| 16 | VRDN | VIRIDIAN THERAPEUTICS INC | $123.5M | 2.31% | 6.7M | Added |
| 17 | OLMA | OLEMA PHARMACEUTICALS INC | $108.5M | 2.03% | 8.7M | Added |
| 18 | JBIO | JADE BIOSCIENCES INC | $63.5M | 1.19% | 2.9M | New |
| 19 | TYRA | TYRA BIOSCIENCES INC | $58.4M | 1.09% | 1.8M | Trimmed |
| 20 | ASMB | ASSEMBLY BIOSCIENCES INC | $42.7M | 0.80% | 1.6M | Added |
| 21 | EYPT | EYEPOINT INC | $41.3M | 0.77% | 2.9M | Trimmed |
| 22 | ACHV | ACHIEVE LIFE SCIENCE INC | $32.3M | 0.61% | 5.0M | New |
| 23 | VOR | VOR BIOPHARMA INC | $32.2M | 0.60% | 1.8M | Hold |
| 24 | MPLT | MAPLIGHT THERAPEUTICS INC | $24.6M | 0.46% | 685,852 | New |
| 25 | KARD | KARDIGAN INC | $21.5M | 0.40% | 900,000 | New |
Source: SEC Form 13F filings · as of 2026-06-30