3 institutions reported holding $58,861 of SPYRE THERAPEUTICS INC (SYRE) in SEC 13F filings for 2026-06-30. Largest institutional holders: GAMMA Investing LLC ($58,861), Assenagon Asset Management S.A. ($0), MassMutual Private Wealth & Trust, FSB ($0). Source: SEC Form 13F.
| Rank | Institution | Value | Shares | Change |
|---|---|---|---|---|
| 1 | GAMMA Investing LLC | $58,861 | 663 | Added |
| 2 | Assenagon Asset Management S.A. | $0 | 0 | Exited |
| 3 | MassMutual Private Wealth & Trust, FSB | $0 | 0 | Exited |
Source: SEC Form 13F filings · as of 2026-06-30