21 insiders reported 392 Form 4 transactions for IONIS PHARMACEUTICALS INC (IONS) over the past 18 months (most recent 2026-07-06). Recent activity: KLEIN JOSEPH III (Director) Sell 99 shares, KLEIN JOSEPH III (Director) Buy 11,518 shares, KLEIN JOSEPH III (Director) Sell 11,419 shares, O'NEIL PATRICK R. (EVP CLO & General Counsel) Sell 3,069 shares, Baroldi Joseph (EVP, Chief Business Officer) Buy 3,866 shares. Source: SEC Form 4.
| Date | Insider | Title | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-07-06 | KLEIN JOSEPH III | Director | Sell | 99 | $7,866 |
| 2026-07-06 | KLEIN JOSEPH III | Director | Buy | 11,518 | $460,029 |
| 2026-07-06 | KLEIN JOSEPH III | Director | Sell | 11,419 | $902,551 |
| 2026-06-30 | O'NEIL PATRICK R. | EVP CLO & General Counsel | Sell | 3,069 | $245,520 |
| 2026-06-30 | Baroldi Joseph | EVP, Chief Business Officer | Buy | 3,866 | $219,511 |
| 2026-06-30 | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | Buy | 26,000 | $1.6M |
| 2026-06-30 | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | Sell | 26,000 | $2.1M |
| 2026-06-30 | Baroldi Joseph | EVP, Chief Business Officer | Buy | 1,769 | $57,669 |
| 2026-06-30 | Baroldi Joseph | EVP, Chief Business Officer | Sell | 5,635 | $451,699 |
| 2026-06-26 | Monia Brett P | Chief Executive Officer | Buy | 21,072 | $686,947 |
| 2026-06-26 | Swayze Eric | EVP Research | Sell | 10,602 | $839,492 |
| 2026-06-26 | Monia Brett P | Chief Executive Officer | Sell | 14,565 | $1.1M |
| 2026-06-26 | Monia Brett P | Chief Executive Officer | Buy | 14,565 | $474,819 |
| 2026-06-26 | Monia Brett P | Chief Executive Officer | Sell | 21,072 | $1.7M |
| 2026-06-26 | Monia Brett P | Chief Executive Officer | Buy | 50,000 | $2.8M |
| 2026-06-26 | Monia Brett P | Chief Executive Officer | Sell | 50,000 | $4.0M |
| 2026-06-16 | BERTHELSEN SPENCER R | Director | Buy | 8,000 | $195,360 |
| 2026-06-16 | Kordasiewicz Holly B. | EVP, Chief Development Officer | Buy | 7,951 | $484,136 |
| 2026-06-16 | BERTHELSEN SPENCER R | Director | Sell | 8,000 | $587,920 |
| 2026-06-16 | Kordasiewicz Holly B. | EVP, Chief Development Officer | Buy | 12,000 | $391,200 |
| 2026-06-16 | Kordasiewicz Holly B. | EVP, Chief Development Officer | Buy | 19,895 | $1.1M |
| 2026-06-16 | Kordasiewicz Holly B. | EVP, Chief Development Officer | Sell | 41,004 | $3.0M |
| 2026-06-16 | Kordasiewicz Holly B. | EVP, Chief Development Officer | Sell | 19,842 | $1.5M |
| 2026-06-16 | Kordasiewicz Holly B. | EVP, Chief Development Officer | Buy | 21,000 | $1.3M |
| 2026-06-03 | BERTHELSEN SPENCER R | Director | Buy | 8,000 | $195,360 |
Source: SEC Form 4 filings · as of 2026-07-06