12 insiders reported 28 Form 4 transactions for Prelude Therapeutics Inc (PRLD) over the past 18 months (most recent 2026-04-28). Recent activity: RA Capital Healthcare Fund LP (10% Owner) Sell 1.4M shares, RA CAPITAL MANAGEMENT, L.P. (10% Owner) Sell 1.4M shares, Kolchinsky Peter (10% Owner) Sell 1.4M shares, Shah Rajeev M. (10% Owner) Sell 1.4M shares, OrbiMed Capital GP VI LLC (Director) Buy 1.1M shares. Source: SEC Form 4.
| Date | Insider | Title | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-04-28 | RA Capital Healthcare Fund LP | 10% Owner | Sell | 1.4M | $0 |
| 2026-04-28 | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Sell | 1.4M | $0 |
| 2026-04-28 | Kolchinsky Peter | 10% Owner | Sell | 1.4M | $0 |
| 2026-04-28 | Shah Rajeev M. | 10% Owner | Sell | 1.4M | $0 |
| 2026-04-23 | OrbiMed Capital GP VI LLC | Director | Buy | 1.1M | $5.0M |
| 2026-04-23 | ORBIMED CAPITAL LLC | Director | Buy | 1.7M | $7.5M |
| 2026-04-23 | ORBIMED ADVISORS LLC | Director | Buy | 1.7M | $7.5M |
| 2026-04-23 | OrbiMed Capital GP VI LLC | Director | Buy | 1.7M | $7.5M |
| 2026-04-23 | OrbiMed Genesis GP LLC | Director | Buy | 1.7M | $7.5M |
| 2026-04-23 | ORBIMED ADVISORS LLC | Director | Buy | 1.1M | $5.0M |
| 2026-04-23 | ORBIMED CAPITAL LLC | Director | Buy | 1.1M | $5.0M |
| 2026-04-23 | Bonita David P | Director | Buy | 1.1M | $5.0M |
| 2026-04-23 | Bonita David P | Director | Buy | 1.7M | $7.5M |
| 2026-04-23 | OrbiMed Genesis GP LLC | Director | Buy | 1.1M | $5.0M |
| 2025-10-07 | Huang Jane | President, CMO | Buy | 9,375 | $0 |
| 2025-10-07 | Huang Jane | President, CMO | Sell | 3,355 | $4,932 |
| 2025-07-08 | Huang Jane | President, CMO | Buy | 9,375 | $0 |
| 2025-07-08 | Huang Jane | President, CMO | Sell | 3,355 | $2,650 |
| 2025-04-07 | Huang Jane | President, CMO | Buy | 9,375 | $0 |
| 2025-04-07 | Huang Jane | President, CMO | Sell | 3,355 | $2,281 |
| 2025-03-27 | Combs Andrew | Chief Chemistry Officer | Buy | 100,000 | $69,000 |
| 2025-03-27 | Vaddi Krishna | CEO | Buy | 675,000 | $465,750 |
| 2025-03-24 | Vaddi Krishna | CEO | Buy | 5,416 | $3,954 |
| 2025-03-24 | Vaddi Krishna | CEO | Buy | 15,000 | $10,950 |
| 2025-03-18 | Vaddi Krishna | CEO | Buy | 29,999 | $22,499 |
Source: SEC Form 4 filings · as of 2026-04-28