Terminal · Institutions

Every 13F-reported equity position this quarter, with its quarter-over-quarter change — each row traces back to the SEC filing.

ARCH Venture Management, LLC 13F Holdings -- Portfolio & Top Positions (2026-06-30)

ARCH Venture Management, LLC (CIK 1274403) reported $1.10B across 12 reported positions in its SEC 13F filing for 2026-06-30. Largest positions: PBLS ($175.5M, 15.95%), BEAM ($155.8M, 14.16%), RAPP ($155.4M, 14.12%), SPTX ($136.6M, 12.42%), ERAS ($129.9M, 11.81%). Source: SEC Form 13F.

RankTickerCompanyValue% PortfolioSharesAction
1PBLSPARABILIS MEDICINES INC$175.5M15.95%6.4MNew
2BEAMBEAM THERAPEUTICS INC$155.8M14.16%4.5MHold
3RAPPRAPPORT THERAPEUTICS INC$155.4M14.12%3.7MHold
4SPTXSEAPORT THERAPEUTICS INC$136.6M12.42%6.3MNew
5ERASERASCA INC$129.9M11.81%7.1MHold
6VIRVIR BIOTECHNOLOGY INC$129.4M11.76%12.7MTrimmed
7MAZEMAZE THERAPEUTICS INC$123.0M11.18%4.1MHold
8LYELLYELL IMMUNOPHARMA INC$45.5M4.14%3.2MHold
9GENBGENERATE BIOMEDICINES INC$32.8M2.98%1.9MHold
10TXG10X GENOMICS INC$8.4M0.76%217,834Hold
11BOLDBOUNDLESS BIO INC$6.7M0.61%2.7MNew
12GOSSGOSSAMER BIO INC$1.3M0.12%8.1MHold
13QTTBQ32 BIO INC$00.00%0Exited

Source: SEC Form 13F filings · as of 2026-06-30