| 1 | EQT Fund Management S.a r.l. | $70.3M | 5.3M | Added |
| 2 | RA CAPITAL MANAGEMENT, L.P. | $46.4M | 3.5M | Hold |
| 3 | PRICE T ROWE ASSOCIATES INC /MD/ | $25.8M | 1.9M | Added |
| 4 | Pivotal bioVenture Partners Investment Advisor LLC | $25.6M | 1.9M | Hold |
| 5 | JPMORGAN CHASE & CO | $23.4M | 1.6M | Added |
| 6 | RTW INVESTMENTS, LP | $20.0M | 1.5M | Hold |
| 7 | Nan Fung Group Holdings Ltd | $19.2M | 1.4M | Hold |
| 8 | Point72 Asset Management, L.P. | $19.1M | 1.4M | Added |
| 9 | ANDERA PARTNERS | $18.5M | 1.4M | Trimmed |
| 10 | EVENTIDE ASSET MANAGEMENT, LLC | $16.1M | 1.2M | Hold |
| 11 | VANGUARD GROUP INC | $14.6M | 1.1M | Added |
| 12 | Vestal Point Capital, LP | $13.3M | 1.0M | New |
| 13 | Jupiter Topco LLC | $11.9M | 896,700 | New |
| 14 | BlackRock, Inc. | $11.8M | 886,538 | Added |
| 15 | BAKER BROS. ADVISORS LP | $11.3M | 847,390 | Hold |
| 16 | Defilade Capital Management, L.P. | $10.5M | 793,145 | Added |
| 17 | AMERICAN CENTURY COMPANIES INC | $10.0M | 755,018 | Added |
| 18 | Alyeska Investment Group, L.P. | $9.4M | 704,425 | Trimmed |
| 19 | Balyasny Asset Management L.P. | $8.3M | 627,015 | New |
| 20 | Affinity Asset Advisors, LLC | $6.6M | 500,100 | New |
| 21 | Velan Capital Investment Management LP | $6.0M | 451,255 | Added |
| 22 | UBS Group AG | $5.5M | 413,553 | Added |
| 23 | FEDERATED HERMES, INC. | $4.3M | 325,000 | Hold |
| 24 | GREAT POINT PARTNERS LLC | $4.3M | 325,000 | Hold |
| 25 | Freestone Grove Partners LP | $4.1M | 306,328 | Trimmed |