8 insiders reported 73 Form 4 transactions for Spyre Therapeutics, Inc. (SYRE) over the past 18 months (most recent 2026-07-02). Recent activity: Turtle Cameron (Chief Executive Officer) Sell 10,176 shares, Burrows Scott L (Chief Financial Officer) Buy 7,500 shares, Sloan Sheldon (Chief Medical Officer) Buy 8,334 shares, Turtle Cameron (Chief Executive Officer) Sell 4,234 shares, Burrows Scott L (Chief Financial Officer) Sell 5,775 shares. Source: SEC Form 4.
| Date | Insider | Title | Type | Shares | Value |
|---|---|---|---|---|---|
| 2026-07-02 | Turtle Cameron | Chief Executive Officer | Sell | 10,176 | $889,789 |
| 2026-07-02 | Burrows Scott L | Chief Financial Officer | Buy | 7,500 | $108,750 |
| 2026-07-02 | Sloan Sheldon | Chief Medical Officer | Buy | 8,334 | $228,852 |
| 2026-07-02 | Turtle Cameron | Chief Executive Officer | Sell | 4,234 | $373,100 |
| 2026-07-02 | Burrows Scott L | Chief Financial Officer | Sell | 5,775 | $505,601 |
| 2026-07-02 | Sloan Sheldon | Chief Medical Officer | Sell | 6,500 | $568,880 |
| 2026-07-02 | Turtle Cameron | Chief Executive Officer | Sell | 590 | $52,457 |
| 2026-07-02 | Burrows Scott L | Chief Financial Officer | Sell | 1,725 | $152,438 |
| 2026-07-02 | Sloan Sheldon | Chief Medical Officer | Sell | 1,834 | $162,016 |
| 2026-06-26 | Burrows Scott L | Chief Financial Officer | Sell | 5,000 | $435,600 |
| 2026-06-26 | Burrows Scott L | Chief Financial Officer | Buy | 15,000 | $217,500 |
| 2026-06-26 | Burrows Scott L | Chief Financial Officer | Sell | 10,000 | $871,400 |
| 2026-06-23 | Fairmount Healthcare Fund II L.P. | Director | Buy | 666,680 | $0 |
| 2026-06-23 | HENDERSON MICHAEL THOMAS | Director | Sell | 20,000 | $2.0M |
| 2026-06-23 | Fairmount Funds Management LLC | Director | Buy | 666,680 | $0 |
| 2026-06-23 | Kiselak Tomas | Director | Buy | 666,680 | $0 |
| 2026-06-23 | Harwin Peter Evan | Director | Sell | 4.7M | $399.7M |
| 2026-06-23 | Fairmount Healthcare Fund II L.P. | Director | Sell | 4.7M | $399.7M |
| 2026-06-23 | Fairmount Funds Management LLC | Director | Sell | 4.7M | $399.7M |
| 2026-06-23 | Kiselak Tomas | Director | Sell | 4.7M | $399.7M |
| 2026-06-23 | Harwin Peter Evan | Director | Buy | 666,680 | $0 |
| 2026-06-03 | Turtle Cameron | Chief Executive Officer | Sell | 8,149 | $574,504 |
| 2026-06-03 | Turtle Cameron | Chief Executive Officer | Sell | 3,557 | $246,856 |
| 2026-06-03 | Burrows Scott L | Chief Financial Officer | Buy | 7,500 | $108,750 |
| 2026-06-03 | Sloan Sheldon | Chief Medical Officer | Buy | 8,333 | $228,824 |
Source: SEC Form 4 filings · as of 2026-07-02