Spruce Street Capital LP 13F Holdings · Q2 2026
Spruce Street Capital LP reported 30 securities worth $509.68M in its SEC 13F filing for Q2 2026 (period ended 2026-06-30). Top holdings: KNSA (11.52%), RLAY (10.95%), LBRX (8.76%). Among its top 25 positions this quarter: 4 new, 8 added, 1 trimmed.
| Rank | Ticker | Company | Value | % Portfolio | Shares | Action |
|---|---|---|---|---|---|---|
| 1 | KNSA | KINIKSA PHARMACEUTICALS INTL | $58.7M | 11.52% | 918,070 | Added |
| 2 | RLAY | RELAY THERAPEUTICS INC | $55.8M | 10.95% | 3.0M | Hold |
| 3 | LBRX | LB PHARMACEUTICALS INC | $44.7M | 8.76% | 1.4M | Hold |
| 4 | RLMD | RELMADA THERAPEUTICS INC | $44.2M | 8.68% | 6.4M | Added |
| 5 | ANRO | ALTO NEUROSCIENCE INC | $35.7M | 7.01% | 1.4M | Added |
| 6 | DNTH | DIANTHUS THERAPEUTICS INC | $34.6M | 6.79% | 354,816 | Trimmed |
| 7 | ALKS | ALKERMES PLC | $28.5M | 5.59% | 543,876 | Added |
| 8 | SVRA | SAVARA INC | $21.3M | 4.17% | 3.5M | Added |
| 9 | PCVX | VAXCYTE INC | $17.8M | 3.49% | 306,047 | Added |
| 10 | ELVN | ENLIVEN THERAPEUTICS INC | $16.7M | 3.28% | 329,006 | Hold |
| 11 | ENTA | ENANTA PHARMACEUTICALS INC | $15.9M | 3.11% | 1.1M | Added |
| 12 | CATX | PERSPECTIVE THERAPEUTICS INC | $12.6M | 2.47% | 3.7M | Added |
| 13 | IFRX | INFLARX NV | $12.0M | 2.35% | 5.4M | New |
| 14 | SRZN | SURROZEN INC | $11.2M | 2.20% | 432,040 | Hold |
| 15 | ALMS | ALUMIS INC | $11.0M | 2.17% | 392,574 | Hold |
| 16 | IPSC | CENTURY THERAPEUTICS INC | $9.9M | 1.95% | 4.1M | Hold |
| 17 | NERV | MINERVA NEUROSCIENCES INC | $9.2M | 1.80% | 1.7M | Hold |
| 18 | SABS | SAB BIOTHERAPEUTICS INC | $8.6M | 1.68% | 2.2M | Hold |
| 19 | ANTX | AN2 THERAPEUTICS INC | $8.0M | 1.58% | 1.7M | Hold |
| 20 | ERAS | ERASCA INC | $7.7M | 1.52% | 422,543 | Hold |
| 21 | IKT | INHIBIKASE THERAPEUTICS INC | $7.3M | 1.43% | 3.6M | Hold |
| 22 | RACC | RESEARCH ALLIANCE CORP III | $5.3M | 1.05% | 500,000 | New |
| 23 | HLXC | HELIX ACQUISITION CORP III | $5.3M | 1.04% | 500,000 | Hold |
| 24 | ZLAB | ZAI LAB LTD | $5.3M | 1.04% | 279,110 | New |
| 25 | ACHV | ACHIEVE LIFE SCIENCE INC | $4.8M | 0.94% | 736,637 | New |
Source: SEC Form 13F filings · as of 2026-06-30
Every position in this 13F-HR, with its change from the prior quarter.
13F holdings, latest quarter
SourceSEC EDGAR13F-HR